Ikkα inhibition re-sensitizes acquired adriamycin-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

HIGHLIGHTS

  • who: Jian Liao from the DepartmentMedical University have published the research work: IKKu03b1 inhibition re-sensitizes acquired adriamycin-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis, in the Journal: Scientific Reports Scientific Reports
  • how: The final IKKu03b1 results were obtained by multiplying the extent of staining with the intensity scores resulting in an IRS score between 0 and 12. Immunohistochemical results showed that IKKu03b1 expression was significantly high in the residual TNBC tissue after NAC than in the TNBC tumor tissue before NAC.

SUMMARY

    Adriamycin-resistant MDA-MB-231 . . .

     

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