Il-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice

HIGHLIGHTS

• who: Jing Ye and Jun Wan from the Temple University, United States have published the Article: IL-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice, in the Journal: (JOURNAL)
• what: The authors aimed to identify the function of IL12p40 in sepsis-induced cardiac dysfunction and to explore its underlying mechanisms. The authors detected that IL-12p40 expression in the hearts of mice was upregulated within 6 h after treatment with LPS; however, after 12 h, the expression of IL-12p40 showed a downwards trend.
• how: This process was repeated several times until . . .
  

   

  

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