Il-17b alleviates the pathogenesis of systemic lupus erythematosus by inhibiting fasn-mediated differentiation of b cells

HIGHLIGHTS

  • What: The authors investigated the role of IL-17B in the activation and differentiation of B cells and the pathogenesis of SLE.
  • Who: Yucai Xiao et al. from the Shandong University, Jining, Shandong, China have published the paper: IL-17B alleviates the pathogenesis of systemic lupus erythematosus by inhibiting FASN-mediated differentiation of B cells Cheeloo, in the Journal: (JOURNAL)
  • How: As FASN is abnormally highly expressed in SLE patients and lipid metabolism plays a key role in the pathogenesis of SLE the authors conducted a comprehensive lipidomic analysis of serum samples obtained . . .

     

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