HIGHLIGHTS
- who: Shuang Liu from the Department of Computer Sciences, University of Wisconsin, Madison, Madison, WI, USA have published the article: Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex, in the Journal: (JOURNAL)
- what: The authors show that trans-regulatory mechanisms provide valuable insights into psychiatric disorders: beyond what had been possible using only cis-eQTLs the authors link an additional 23 GWAS loci 90 risk genes (using colocalization candidate trans-eQTLs schizophrenia GWAS loci). The authors demonstrate that the transcriptional architecture of the human brain is orchestrated by both . . .
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