Imaging cxcr4 expression with iodinated and brominated cyclam derivatives

HIGHLIGHTS

  • who: Hanwen Zhang from the Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA Department of Nuclear Medicine, Technical University Munich, Munich, Germany have published the research: Imaging CXCR4 Expression with Iodinated and Brominated Cyclam Derivatives, in the Journal: (JOURNAL)
  • what: The main focus of current study was to develop radiolabeled the derivatives of Plerixafor and AMD3465 that crosses the BBB and tumor cell membranes for PET imaging of CXCR4. The authors show that such modifications have no or minimal effect on binding to the CXCR4 target.
  • how: Considering that . . .

     

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