Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

HIGHLIGHTS

  • who: Sari Tu00e4hku00e4 from the Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Viikinkaari E, Helsinki, Finland have published the research work: Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction, in the Journal: (JOURNAL)
  • what: The authors demonstrate the immobilization of u03b1-chymotrypsin (CHT) onto GNP-coated thiol-ene S. Tu00e4hku00e4 et_al micropillars via the enzyme`s free thiol groups (reduced disulfide_bridges). The authors examined the possibilities of exploiting the inherent high thiol density of the crosslinked offstoichiometric (thiol-rich) thiol . . .

     

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