Immune activation during pregnancy exacerbates asd-related alterations in

HIGHLIGHTS

  • who: Ekaterina Atanasova from the Institute for Anatomy and Cell Biology, University, Germany have published the research: Immune activation during pregnancy exacerbates ASD-related alterations in, in the Journal: (JOURNAL)
  • what: The authors show that the two-hit mice exhibit excessive grooming and deficits in social behavior more prominently than the Shank3u039411-/- mice. With this study the authors demonstrate that there is an interplay between genetic susceptibility and environu2011 mental factors defining the severity of ASD symptoms. The authors show that a general misbalance of PSD proteins at excitatory synapses is linked to ASD symptoms . . .

     

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