Immune cell metabolic fitness for life

HIGHLIGHTS

  • who: Kevin S. Bittman from the (UNIVERSITY) have published the Article: Immune Cell Metabolic Fitness for Life, in the Journal: Antibodies 2022, 11, 32. of /2022/
  • future: The various T Cell subtypes differ in the nature of energy maintenance and production and offer some key findings to drive future breakthroughs in immuno-oncology.

SUMMARY

    So, although the original concepts for engineering a CAR T_cell for fighting cancer focused on the intracellular signaling that induced activation and persistence, without the right bioenergetics, the newly made CAR T_cell will not get the job . . .

     

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