Immune dysfunction following severe trauma: a systems failure from the central nervous system to mitochondria

HIGHLIGHTS

  • who: Geoffrey P. Dobson from the University Hospital RWTH Aachen, Germany have published the research: Immune dysfunction following severe trauma: A systems failure from the central nervous system to mitochondria, in the Journal: (JOURNAL)
  • what: In this review, the aim is to discuss the inflammatory and immune mechanisms that are believed to be responsible for early and late secondary injuries and death following traumatic injury, and possible ways to reduce morbidity and mortality from a systemsbased perspective.
  • future: Future studies should include proteomic and pathway-level analysis to establish the different roles of . . .

     

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