HIGHLIGHTS
- who: Francesco Baccelli from the (UNIVERSITY) have published the Article: Immune dysregulation associated with co-occurring germline, in the Journal: (JOURNAL)
- future: Studies are needed to understand the exact contribution of the immune system endothelium and coagulation system in the biology of vascular damage in CBL syndrome.
SUMMARY
Patients with RASopathies are known to be at increased risk of cancer development, CBL syndrome is associated with an increased risk of JMML and CBL mutations occurs in of a variety of myeloid neoplasms. Leukemogenesis in germ-line mutations is mainly related to . . .
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