Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

HIGHLIGHTS

  • who: Immune-interacting lymphatic endothelial subtype et al. from the (UNIVERSITY) have published the article: Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation, in the Journal: (JOURNAL) of 02/02/2023

SUMMARY

    Venous malformations (VMs) and lymphatic malformations (LMs) are chronic diseases characterized by vascular lesions that range from simple skin discoloration to large deformations, or fluid-filled cysts to infiltrative soft-tissue masses, respectively (Queisser et_al, 2021; Màˆkinen et_al, 2021). Somatic-activating PIK3CA mutations have been identified as causative of the majority of LMs (Luks et_al, 2015; Osborn . . .

     

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