Immune profiles according to egfr mutant subtypes and correlation with pd-1/pd-l1 inhibitor therapies in lung adenocarcinoma

HIGHLIGHTS

• who: Young Wha Koh and colleagues from the the Institutional Review Board of Ajou University School ofGermany have published the paper: Immune profiles according to EGFR mutant subtypes and correlation with PD-1/PD-L1 inhibitor therapies in lung adenocarcinoma, in the Journal: (JOURNAL)
• what: The authors investigated the distributions of 22 immune cells according to the presence or absence of EGFR mutations using two public LUAD gene_expression datasets and the CIBERSORTx tool.

SUMMARY

Patients with EGFR-mutated NSCLC lack Tcell infiltration and have decreased ratios of PD-L1+/CD8+ tumorinfiltrating . . .

 



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