Immune-related potential biomarkers and therapeutic targets in coronary artery disease

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SUMMARY

    From the perspective of the primary prevention of CAD, the concern is whether new risk markers for atherosclerosis can improve CAD risk prediction. The authors developed a new diagnostic model of optimal feature genes (OFGs) using differentially expressed immune-related genes (DE-IRGs) in CAD patients. Gene expression information for CAD and standard samples was retrieved from the Gene Expression Omnibus (GEO) database. Analysis (ssGSEA) and single-gene gene set variation analysis (ssGSVA) Gene set enrichment analysis (GSEA) is a popular framework for condensing information in gene_expression profiles into pathways or signature summaries. Infiltration . . .

     

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