Immunogenetics associated with severe coccidioidomycosis

HIGHLIGHTS

  • who: Amy P. Hsu and colleagues from the LaboratoryUniversity of, Chengdu, Sichuan Province, China have published the research: Immunogenetics associated with severe coccidioidomycosis, in the Journal: (JOURNAL)
  • what: 16 Several variants identified in the study have been previously implicated in fungal disease or immune dysregulation. Similar to these studies, the authors demonstrate the roles of common population variants which are benign unless the carrier is infected with a geographicallyisolated, pathogenic organism, Coccidioides.
  • how: The association was first examined in the discovery matched cohort and the significant gene was tested in the validation cohort . . .

     

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