Immunogenicity of wild type and mutant hepatitis b surface antigen virus-like particles (vlps) in mice with pre-existing immunity against the wild type vector

HIGHLIGHTS

• who: Natalie J. Kingston and colleagues from the Monash University, Clayton, VIC, Australia have published the research work: Immunogenicity of Wild Type and Mutant Hepatitis B Surface Antigen Virus-like Particles (VLPs) in Mice with Pre-Existing Immunity against the Wild Type Vector, in the Journal: Viruses 2023, 15, 313. of 31/Dec/2022
• what: 8 of 14 With the absence of significant levels of anti-HBsAgS antibodies in the mice immunized with M15-HBsAgS VLPs, the authors aimed to confirm that the M15-HBsAgS VLPs had retained their immunogenicity.

SUMMARY

 



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