Immunohistochemical based molecular subtypes of muscle-invasive bladder cancer: association with her2 and egfr alterations, neoadjuvant chemotherapy response and survival

HIGHLIGHTS

  • who: Duaa S. Helal from the Pathology Department, Faculty of Medicine, University have published the research work: Immunohistochemical based molecular subtypes of muscle-invasive bladder cancer: association with HER2 and EGFR alterations, neoadjuvant chemotherapy response and survival, in the Journal: (JOURNAL)
  • what: The aim of this work was to identify the molecular subtype of MIBC cases using the immunohistochemical markers; GATA3, CK5/6 and p53 and study their prognostic significance in relation to clinicopathologic parameters,survival and response to NAC treatment. Histologically, all luminal tumors in this study showed conventional urothelial morphology while basal tumors . . .

     

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