Immunoinformatic analysis of the whole proteome for vaccine design: an application to clostridium perfringens

HIGHLIGHTS

  • who: Luis F. Soto from the Emory University, United States have published the article: Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens, in the Journal: (JOURNAL)
  • what: (F) Structural alignment between the AlphaFold2 model (gray) and the centroid of the most populated cluster (in orange) of MEP_12. this model has a good resolution. Noteworthy, the authors show the relevance of not only predicting promiscuous epitopes but studying their location within the proteins as well. Whilst the study of Aldakheel et_al attempted to target all HLA-I and -II alleles . . .

     

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