Immunometabolism in cancer at a glance

HIGHLIGHTS

• who: AT A, GLANCE and SPECIAL COLLECTION, CANCER METABOLISM from the It has long been known that cancer cells hijack cellular programs that regulate survival, growth and proliferation, leading to tumor formation and progressionThe best-known causes of malignant transformation are the genetic and epigenetic changes that induce stem-cell-like properties, such as unlimited cell division and blocked differentiation. Traditionally, the proposed role of the cellular metabolism of cancer cells was to primarily support and sustain malignant growth. However, it is clear today that cellular metabolism actively regulates the malignant phenotype. For example, loss of the . . .
  

   

  

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