Immunomodulation of hdac inhibitor entinostat potentiates the anticancer effects of radiation and pd-1 blockade in the murine lewis lung carcinoma model

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  • who: Yeeun Kim and colleagues from the Department of Radiation Oncology, Samsung Medical Center, Seoul, Republic of Korea Department of Radiation Oncology, Sungkyunkwan University School of Medicine have published the article: Immunomodulation of HDAC Inhibitor Entinostat Potentiates the Anticancer Effects of Radiation and PD-1 Blockade in the Murine Lewis Lung Carcinoma Model, in the Journal: (JOURNAL) of 18/Oct/2019
  • what: The authors showed that the histone deacetylase inhibitor entinostat potentiated the efficacy of radiotherapy and anti-PD-1 using a murine syngeneic LL/2 tumor model.
  • how: The authors investigated whether . . .

     

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