Immunophenotyping of acute in fl ammatory exacerbations of lung injury driven by mutant surfactant protein-c: a role for in ammatory eosinophils

HIGHLIGHTS

  • who: (SP-C et al. from the Chiesi Farmaceutici, Italy Old Dominion University have published the article: Immunophenotyping of Acute In fl ammatory Exacerbations of Lung Injury Driven by Mutant Surfactant Protein-C: A Role for In ammatory Eosinophils, in the Journal: (JOURNAL)
  • what: The authors show that inflammatory exacerbations triggered by a PF-linked mutation of the surfactant protein C (SP-CI73T) produce an eosinophilic phenotype. The authors characterize the benefits of eosinophil lineage deletion and standard corticosteroid therapy in eosinophilic AIEs.
  • how: Quality_control processing was conducted with the Seurat (4.0 . . .

     

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