Immunosenescence and immunotherapy in elderly acute myeloid leukemia patients: time for a biology-driven approach

HIGHLIGHTS

  • who: Alessandro Isidori et al. from the Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "Land A have published the paper: Immunosenescence and Immunotherapy in Elderly Acute Myeloid Leukemia Patients: Time for a Biology-Driven Approach, in the Journal: (JOURNAL)
  • what: Under this viewpoint, the authors propose that the underlying background of immunosenescence should be specifically addressed in future clinical trials, where novel immunotherapies are used .

SUMMARY

    Aging is associated with two important changes in T_cell subpopulations: a decrease in naïve T_cells, mainly due to combined thymic involution . . .

     

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