Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing

HIGHLIGHTS

• who: Yi Bai from the University of Bologna Department of Medical and Surgical Sciences, Italy have published the research: Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing, in the Journal: (JOURNAL)
• what: In this study, the gene set enrichment of each cell cluster was determined by gene set enrichment analysis (GSEA). The authors investigated the TIME of HCC using single-cell_sequencing and revealed the landscape of major immune cell types. The research provides a novel theoretical basis for modulating the TIME in HCC and will aid the development of new immunotherapies.
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