Immunotherapy with cleavage-specific 12a12mab reduces the tau cleavage in visual cortex and improves visuo-spatial recognition memory in tg2576 ad mouse model

HIGHLIGHTS

• who: Valentina Latina and collaborators from the European Brain Research Institute (EBRI), Viale Elena, Rome, Italy have published the article: Immunotherapy with Cleavage-Specific 12A12mAb Reduces the Tau Cleavage in Visual Cortex and Improves Visuo-Spatial Recognition Memory in Tg2576 AD Mouse Model, in the Journal: Pharmaceutics 2023, 509 of 18/04/2008
• what: The authors report the occurrence of N-terminal tau in the primary visual (V1 area) and the beneficial effect of 12A12mAb treatment on phenotype-associated deficits in this AD animal model. In this framework, in this study the authors explored whether . . .
  

   

  

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