Imp is required for timely exit from quiescence in drosophila type ii neuroblasts

HIGHLIGHTS

SUMMARY

One way to help understand oRG lineages is to use model organisms that contain neural stem_cells with lineages similar to oRGs, which can be used to generate testable hypotheses for investigating primate oRG lineages. In Drosophila, there is a small pool of 16 neural stem_cells in the brain (eight stem_cells per brain lobe), called type II neuroblasts (TIINBs), that undergo a lineage similar to primate oRGs to generate neurons (Fig 1A). Imp regulates neuroblast exit from quiescence generate neurons of the cortex; in Drosophila the TIINBs generate neurons of the adult central complex (CX . . .

 



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