Impact of betamethasone pretreatment on engrafment of cord blood-derived hematopoietic stem cells

HIGHLIGHTS

  • who: David Perna-Barrull from the Immunology Department, Germans Trias I Pujol Research Institute, Autonomous University of Barcelona, Badalona, Spain have published the article: Impact of Betamethasone Pretreatment on Engrafment of Cord Blood-Derived Hematopoietic Stem Cells, in the Journal: (JOURNAL)
  • what: The authors provide a strategy to improve the engraftment capacities of UCB stem_cells using betamethasone as a preconditioning treatment. The authors show that cord blood C u00ad D34+ hematopoietic stem_cells (HSC) exposed to betamethasone increase the expression of C-X-C chemokine receptor type 4 (CXCR4) and decrease the expression of HLA class . . .

     

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