Impact of donor pool size on the variability of platelet lysate-derived extracellular vesicles for regenerative medicine

HIGHLIGHTS

• What: The aim of this study was to determine the variability of platelet lysate-derived extracellular vesicles (pEV) in terms of characteristics and functionality through wound healing assays when isolated either from platelet concentrates (PC obtained from 5 donors) or from multiple PC (MPC that is 50 donors). The study of pEV in tissue regeneration has been one of the main objectives of the group . pEV have been shown to have great clinical translatability, with good results in improving osteogenic potentia , regenerative effect for gingival and skin wound healing application and osteoarthriti . The authors investigated the batch . . .
  

   

  

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