Impact of dyrk1a expression on tnnt2 splicing and daunorubicin toxicity in human ipsc-derived cardiomyocytes

HIGHLIGHTS

  • who: Romina Beatriz Cejas from the Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA have published the research: Impact of DYRK1A Expression on TNNT2 Splicing and Daunorubicin Toxicity in Human iPSC-Derived Cardiomyocytes, in the Journal: (JOURNAL)
  • what: The authors investigated the impact of DYRK1A on the endogenous expression of TNNT2 splicing variants in iPSC-derived cardiomyocytes. This study examined DYRK1A-SRSF6-TNNT2 interplays in beating iPSC cardiomyocytes.
  • how: Calibration curves were prepared to analyse linearity and PCR efficiency. qRT . . .

     

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