HIGHLIGHTS
- who: Lucillia Bezu from the Fudan University, China have published the article: Impact of local anesthetics on epigenetics in cancer, in the Journal: (JOURNAL)
SUMMARY
Epigenetic alterations and cancer Epigenetic alterations are common molecular hallmarks of most cancers. In normal cells, epigenetic changes are fundamental for the control of gene_expression, for the maintenance of cellular identities and for acquisition of an ever more differentiated and specialized phenotype. At clinically relevant concentrations, LA inhibit the proliferation of cancer cells by provoking cell cycle arrest, by triggering mitochondrial dysfunction or by causing apoptotic cell death . . .
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