Impact of neurons on patient-derived cardiomyocytes using organ-on-a-chip and ipsc biotechnologies

HIGHLIGHTS

  • who: Albin A. Bernardin et al. from the University of Montpellier, Inserm, CNRS, du Doyen GGiraud, , Montpellier, France have published the research: Impact of Neurons on Patient-Derived Cardiomyocytes Using Organ-On-A-Chip and iPSC Biotechnologies, in the Journal: Cells 2022, 3764 of /2022/
  • what: The authors designed an innovant neuro-cardiac OOC based on microfluidic chip and hiPSC to study the impact of rat sympathetic neurons (differentiated for PC12 cells) or human hiPSC-derived autonomic neurons (hiPSC-NRs) on the functional properties of ventricular-like human hiPSC-derived cardiomyocytes (hiPSC-CMs). This analysis . . .

     

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