Impact of the epoxide hydrolase ephd on the metabolism of mycolic acids in mycobacteria

HIGHLIGHTS

  • who: Jan Madacki from the (UNIVERSITY) have published the research work: Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria, in the Journal: (JOURNAL) of February/16,/2018
  • what: The authors report that the mycobacterial epoxide hydrolase EphD is involved in mycolic acid metabolism. Disruption of ephD in M. tuberculosis impairs biosynthesis of ketomycolic acids By means of overproduction of EphD in M. smegmatis and M. bovis BCG ⌬hma, the authors show that its activity leads to the J. Biol. The authors provided evidence of the involvement of a novel . . .

     

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