Impact of the voltage-gated calcium channel antagonist nimodipine on the development of oligodendrocyte precursor cells

HIGHLIGHTS

  • who: Michael Enders and colleagues from the Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, Germany have published the article: Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells, in the Journal: (JOURNAL)
  • what: The authors examined the effect of nimodipine on oligodendrocyte precursor cells (OPCs), which are a natural reservoir of oligodendrocytes. Patch-clamp experiments were conducted to demonstrate that the detected CaV 1.2 channel was physiologically active .
  • future: Investigation is necessary to identify potential interaction partners of nimodipine at a cellular level . . .

     

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