Impaired glucose homeostasis in a tau knock-in mouse model

HIGHLIGHTS

• who: David Blum from the University Medical Center Goettingen, Germany have published the research work: Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model, in the Journal: (JOURNAL) of 29/Dec/1998
• what: To address this question, in the present study, the authors have investigated the peripheral metabolic outcomes in a new knock-in model of tau loss-of-function, expressing mutated (P301L) human tau protein under the control of the endogenous murine Mapt promoter. Noteworthy, similarly to other KI strains reported (Hashimoto et_al, 2019; Saito et_al, 2019), the present model does not exhibit . . .
  

   

  

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