Impaired interactions of ataxin-3 with protein complexes reveals their specific structure and functions in sca3 ki150 model

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  • who: ufeffPiotrufeff ufeffPiaseckiufeff and collaborators from the Mediterranean Neurological Institute Neuromed (IRCCS), Italy University of Texas Health Science Center at have published the Article: Impaired interactions of ataxin-3 with protein complexes reveals their specific structure and functions in SCA3 Ki150 model, in the Journal: (JOURNAL)
  • what: To understand the SCA3 neuropathomechanism in the model , the authors determined the ataxin-3 interactions by identifying large complexes and proteins responsible for neuronal transport, mitochondria, and translation. The authors aimed to (i) investigate the distribution of ataxin-3 protein in SEC fractions, (ii) identify coeluting ataxin-3 . . .

     

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