Impaired otud7a-dependent ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

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• who: Brianna K. Unda from the Animals Df(h15q13)/+ mice were generated by Taconic Artemis as described previously [24]Animals were bred, genotyped, housed and approved for use at the Central Animal Facility at McMaster University and the Animal Research Ethics Board, and by the Animal Resource Center at the University Health Network in Toronto, Canada. Genotypes were identified during breeding by PCR of ear notches, and two WT females were bred with , Df(h15q13)/+ male per breeding cage. The use of only WT females for breeding was performed to minimize the effects of potential differences in . . .
  

   

  

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