HIGHLIGHTS
- who: Yunhui Zhang from the Department of Orthopedics, The Eighth Affiliated Hospital, Sun Yat-Sen University, # Shennan Road, Shenzhen, People`s Republic of China have published the research: Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis, in the Journal: (JOURNAL)
- what: The authors aimed to explore the mechanisms by which APPL1 alters hMSCs adipogenic differentiation in osteoporosis. The experiments described above showed that APPL1 acts through MYOF, but more research is necessary to confirm how MYOF, the downstream protein of APPL1, affects hMSCs adipogenic differentiation. The . . .
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