Implementation of individualised polygenic risk score analysis: a test case of a family of four

HIGHLIGHTS

  • who: Manuel Corpas from the publishing personal genetic data have published the article: Implementation of individualised polygenic risk score analysis: a test case of a family of four, in the Journal: (JOURNAL) of 24/03/2021
  • what: To compare PRS percentiles between family individuals, the authors compare values relative to the 1000G EUR population distribution. For the purposes of this analysis only, the authors have defined high risk as the individual falling above the 80th percentile of a given background distribution, as this is the threshold from which both Khera et_al and Mars et_al begin . . .

     

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