Implication of intestinal barrier dysfunction in gut dysbiosis and diseases

HIGHLIGHTS

  • who: Carmine Stolfi et al. from the Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy have published the Article: Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases, in the Journal: Biomedicines 2022, 10, 289. of /2022/
  • what: The study has recently demonstrated that conditional deletion of Gata6 in the gut epithelium significantly affected intestinal barrier integrity, leading to decreased expression of the tight junction-related protein zonula occludens-1 (ZO-1), and resulting in increased paracellular permeability, microbial dysbiosis, and susceptibility to gut inflammation .

SUMMARY

    Intestinal . . .

     

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