Implication of oxysterols in infectious and non-communicable inflammatory diseases

HIGHLIGHTS

SUMMARY

    Several oxysterols are involved in the immune_response and can act on infectious agents; their involvement in the immune_response and cytokine storm is very likely, because some of their receptors are associated with immune activities and signaling pathways by which oxysterols 2 of 4 promote cytokine production. The effects of these oxysterols and the LXRs and EBI2 receptors are discussed in the context of the immune_response in the blood and central nervous system. The review by Lisa Reinmuth et_al surveys the two broad classes of cell-surface receptors for oxysterols (G protein-coupled receptors and . . .

     

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