HIGHLIGHTS
- who: Sahar A. Harby from the Department of Clinical Pharmacology, Faculty of Medicine, Alexandria University, Alexandria, Egypt have published the article: Implications of BCRP modulation on PTZ-induced acute seizures in mice: Role of ko143 and metformin as adjuvants to lamotrigine, in the Journal: (JOURNAL)
- what: In this work BCRP`s role as a mechanism that might contribute to drug-resistant epilepsy (DRE) in a mouse model of acute seizures was studied with further assessment of the effect of its inhibition by ko143 and metformin (MET) on lamotrigine (LTG) bioavailability and efficacy. In the present . . .
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