Implications of notch signaling in duchenne muscular dystrophy

HIGHLIGHTS

  • who: September and colleagues from the Jikei University School of Medicine, Japan have published the paper: Implications of notch signaling in duchenne muscular dystrophy, in the Journal: (JOURNAL)
  • what: Orthopedic management and physiotherapy are employed with the primary goals of minimizing joint contractures, maintaining a straight spine, and promoting bone health (Birnkrant et_al, 2018a).
  • how: This review introduces the pathogenesis and treatment strategies for DMD and discusses the biology of the Notch pathway and genetics in muscular dystrophies. large size is its complex mutational spectrum it has a high spontaneous mutation rate and . . .

     

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