Implications of s-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis

HIGHLIGHTS

• who: Paola C. Rosas from the First Hospital, Peking University, China have published the research work: Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis, in the Journal: (JOURNAL)
• what: In view of evidence discussed below that cardiac myosin binding protein C (cMyBP-C), actin, cardiac troponin I (cTnI) and titin are modified by S-glutathionylation, the authors focus here on these sarcomere proteins in physiological control of cardiac function by this oxidative related and potentially maladaptive post-translational modification.
• how: Showed that the cTnIcTnC interaction senses sarcomere length . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.