Implications of the organ-specific immune environment for immune priming effect of radiotherapy in metastatic setting

HIGHLIGHTS

  • who: Julien Pierrard et al. from the (UNIVERSITY) have published the Article: Implications of the Organ-Specific Immune Environment for Immune Priming Effect of Radiotherapy in Metastatic Setting, in the Journal: Biomolecules 2023, 689 of /2023/
  • what: This study evaluated the combination of high- and low-dose RT with continuing ICIs beyond progression in NSCLC and melanoma patients.

SUMMARY

    A wide variety of immune cells exist in the liver sinusoids, including Kuppfer cells, which produce caspase-3 mediated signals to induce T_cells` apoptosis (such as Fas-ligand and TNF-receptor apoptosis . . .

     

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