Implications of trimethylamine n-oxide (tmao) and betaine in human health: beyond being osmoprotective compounds

HIGHLIGHTS

  • who: August et al. from the University of Bari Aldo Moro, Italy have published the paper: Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds, in the Journal: (JOURNAL)

SUMMARY

    The organisms ranging from microbes to higher plants and animals accumulate osmolytes in high concentrations during stress conditions to protect their cellular components (Burg and Ferraris, 2008; Wijayasinghe et_al, 2017). Many osmolytes do not directly interact with proteins but exhibit osmoprotectant activity by excluding them from the protein surface (i.e., osmophobic effect), allowing proteins to fold . . .

     

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