Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes

HIGHLIGHTS

• who: Hasiyet Memetimin from the DivisionUniversity of have published the research: Improved u03b2-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes, in the Journal: Scientific Reports Scientific Reports
• what: To suppression of the cholesterol homeostasis pathway, this analysis identified several pathways that contribute to adipose dysfunction are repressed in AdipoQ-LPL mice including the unfolded protein response (endoplasmic_reticulum stress) and mammalian target of rapamycin complex 1 (MTORC1 signaling) ; example enrichment plots are shown in Fig 1. For the analysis of Ccl19 splicing in_vitro, exon specific primers were . . .
  

   

  

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