Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase r

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  • who: Kangyun Wu et al. from the University School of Medicine, Palo Alto, California, United States of America have published the article: Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R, in the Journal: (JOURNAL) of February/16,/2012
  • what: The authors report that the dsRNAdependent protein kinase (PKR) is such an enzyme. The authors prepared 5 sections evenly spaced through each fixed lung from all mice 24 weeks after infection with Mtb in the experiment shown in Figure 1A. In the studies described here, deletion of PKR apparently led . . .

     

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