Improved efficacy of mesenchymal stromal cells stably expressing cxcr4 and il-10 in a xenogeneic graft versus host disease mouse model

HIGHLIGHTS

  • who: Rosario Hervu00e1s-Salcedo and collaborators from the Germany University of Louisville, United States have published the article: Improved efficacy of mesenchymal stromal cells stably expressing CXCR4 and IL-10 in a xenogeneic graft versus host disease mouse model, in the Journal: (JOURNAL)
  • what: The authors demonstrate that, compared to WT-MSCs, MSCs stably expressing both CXCR4 and IL-10 exert enhanced therapeutic effects in a humanized model of GvHD, strongly suggesting that these cells will constitute a novel advanced therapy medicinal product with enhanced anti-GvHD therapeutic properties. Taken together, the study demonstrates that . . .

     

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