HIGHLIGHTS
- who: Lars Kolbowski et al. from the The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer have published the research: Improved Peptide Backbone Fragmentation Is the Primary Advantage of MS-Cleavable Crosslinkers, in the Journal: (JOURNAL) of May/25,/2022
- what: The authors show furthermore that the intricate MS3-based data acquisition approaches lack sensitivity and specificity causing them to be outperformed by the simpler and faster stepped higher-energy collisional dissociation (HCD) method. understanding will guide future developments and applications of proteome-wide crosslinking mass spectrometry. ■ acid (S . . .
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