HIGHLIGHTS
- who: Hailiang Huang from the Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA of Education), Tong University, China have published the research work: Improving Polygenic Prediction in Ancestrally Diverse Populations, in the Journal: (JOURNAL)
- what: The authors show that PRS-CSx outperforms alternative methods across traits with a wide range of genetic architectures and cross-population genetic correlations in simulations and substantially improves the prediction of quantitative traits and schizophrenia risk in non-European populations.
- how: The authors have used an African reference panel to approximate the LD . . .
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