HIGHLIGHTS
SUMMARY
Scholars have critically argued that the adoption of guidelines in LMICs, in merely attempting to emulate "clinical guidelines developed in rich countries, risks placing unnecessary strains on their health services". WHO policy-makers and guideline developers seek to understand the extent of uptake and how the guidelines are integrated into the policy and practice in LMICs, where the maximum use of WHO guidelines is expected. To optimize uptake and use of WHO`s GRC-approved guidelines, WHO commissioned a review of the literature to contribute to what is known about the uptake and use . . .

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