In good times and in bad: how plasma cells resolve stress for a life-long union with the bone marrow

HIGHLIGHTS

• who: Carolin Ulbricht and collaborators from the University of Massachusetts Medical School, United States have published the research work: In good times and in bad: How plasma cells resolve stress for a life-long union with the bone marrow, in the Journal: nutrients in the densely packed medullary cords lead to transient calcium increase in the cytoplasm, likely through mitochondrial release (54, 55). Second, high production rates of antibodies induce ER-calcium release alongside ER-stress, initiating calcium replenishment from the extracellular environment. One proposed downstream effector of increased cytoplasmic calcium is AMPK. In times of energy . . .
  

   

  

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